Games like Realm of Alters

Yi Xian: The Cultivation Card Game is an online DBG which contains a PVE mode called Uncharted Realms and a PVP mode. Every game is a deck building from scratch. Players can have stronger decks by changing cards, and then build more powerful routines to defeat all opponents to win.

Card game mechanics - check. Real time battles - check. Silly humor - check. If this isn't the game of your dreams i don't know what is (Also we have hidden memes everywhere lol)

E-sports Godfather is a Deck-building game simulating MOBA e-sports. You will play a role as team coach and build your team. You need to train players and make strategies in various game versions, beat other teams and finally, take the Champion of the World. Be nobody, or lead your team to dominate!

Build a deck and battle online in real-time action with rollback netcode!

"Heroes Wanted" immerses you in a world of endless deck-building possibilities. Over a hundred of heroes and items, combined with elements, unleash powerful synergies. SIMPLE, FUN, and ADDICTIVE! Heroes await your call to deliver the ultimate blow to the Demon Lord.

Cross Blitz is a unique RPG deckbuilder featuring fast-paced tactical combat with loads of cards to collect and synergies to wield. Explore, level up, craft new cards and build the perfect decks as you carve your own path to victory!

The most enjoyable Chinese-style Roguelike card game! Play as Cao Cao and conquer the Central, Japanese, and Western waifu with your allies, save the world!

洪荒是一款非常非常非常肝的文字素材类游戏，游戏中没有华丽的美术，闪亮亮的特效，完全以放置挂机的数值玩法为驱动，养成依靠打书、炼妖、修炼、构筑装备品质词条等搭配数百名不同的角色，在其中玩家更能够通过放置挂机获得宝物与资源，拥有各种神话传说中的角色，然后将获得的物品角色与其他玩家进行交易来养成自己最强的阵容。

DICEOMANCER is a roguelike deck-building game. Though you long for a peaceful life, you're forced to embark on an adventure. In this world of swords, magic, and guns, make good use of your dice and deck to find a way back to tranquility! What can the dice be used for? To change... anything.

A fast-paced roguelike kingdom builder. Grow your empire and fight massive battles against powerful rival kings. Break the game with thousands of insane builds to become the King of Kings.

Stray Path is an innovative adventure and strategy game that blends FreeCell mechanics with roguelike gameplay. Choose from colourful characters and explore a randomly generated world. Drag cards, optimize your choices, select equipment, and uncover the mysteries of this mysterious stray world!

"GODSOUL" is a story-driven,Hyper-visually RPG. Team with "rebel" girls who love gaming and drawing（and more）, resist villains and enjoy a mix of cyber reality, fantastical worlds, and card game action.

A free-to-play digital collectible card game set in the 41st millennium, Warpforge brings together the major factions of the Warhammer 40,000 universe as digital cards for players to collect and do battle with in brutal and fast-paced skirmishes.

Noctiria is a horror roguelite deckbuilder set in a decaying 1990s city. Choose one of six heroes, combine brutal status effects, manage your Sanity and consumable relics, and permanently upgrade your arsenal between descents.

Takara Cards is a unique tactical deck-builder RPG about chasing space dragons in a sci-fi fantasy universe. Create your deck as you explore sectors, fighting your way in deep puzzly combat. Every decision you make affects your Ship and Character: Each new adventure offers new surprises!

Yao-Guai Hunter is a Wuxia roguelike deck-building game. In a world where Yao-Guai roam free, player battles with various evil beings, collecting cards and learn inner skills. Encountering various adventures in the martial world.

A hardcore roguelite card game where deck-building strategies are at the core of everything! With a vast array of cards, random dungeons, a wealth of encounter events, and diverse enemies, it awaits your exploration and challenge.

VineCard is a card strategy game that combines war chess and light rogue-like elements. Explore the divine weapons on the Kochab Planet, slay demons, solve puzzles, and cultivate your skills to the utmost.