Games like Protolife

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

The Front is a survival open-world crafting sandbox game. You are a resistance fighter sent back in time to stop the rise of a tyrannical empire. Collect resources, craft tech, build shelters, and fight monsters to accomplish your mission.

Critter Chaos TD is a fast, frantic and chaotic Tower Defence game in which you must rid the world of the evil Critters. Build stations and guns to fortify your defences and prevent the various types of Critters from reaching your base.

2D Strategy game.

Build a castle by day and defend it by night. Becastled blends cozy city-building with challenging tower defense strategy. Lead the Sun Kingdom’s last stand against the Moon Beasts and end the ancient conflict between light and darkness!

Desynced is a sci-fi strategy game with fully customizable units and behaviors. Gather, build, research, and explore the unknown. Alone or with friends, unveil the mystery of an AI on the edge of self-awareness and uncover the hidden truth in this blend of strategy, automation, and exploration.

Golden-age RTS classic. Fast-paced action & strategic decision-making, battling evil arch-enemies, zombies, and retro-futuristic technologies. All to a '90s electro-metal soundtrack and FMV live-action cut scenes.

From a small village of a dozen people to a small kingdom of thousands of people. Arrange for residents to work, gathering, fishing and hunting, farming and mining, processing and manufacturing. Trade, accumulate supplies, increase your strength, and fight evil forces and monsters.

A factory-building game. Survive a harsh climate, strip mine an infinite world, and build a sprawling factory, then trade or go to war with Colonists, Governments, Pirates, Rebels, and more!

Explore endless Universe and create the most efficient constellation of colonies. Build conveyor systems to automate production. Take care of Astronauts and their needs! Establish new colonies as part of intergalactic simulation.

Mine by day, defend by night. Master 25+ spells, sell rare ores for gear upgrades, and grow stronger each run in this procedurally generated roguelite tower defense. Enjoy full controller and Steam Deck support.

The Perfect Tower II is a mix between an incremental and a tower defense game. Build a town, manage resources and explore a variety of mini-games and tons of upgrades. Fully automate your game and watch numbers going up!

Build and manage your own castle settlement in a land reclaimed by wilderness. With detailed management, survival strategy, and a moddable sandbox world, Going Medieval challenges you to build the mightiest colony this side of the apocalypse.

Starship Theory is a ship building survival game. Mine and trade to gather resources. Plan and construct new upgrades. Train and manage crew. Fight to survive.

Embark on a space voyage with your ragtag crew of civilians in search of a new home. Build spaceships tile by tile, create optimal gas conditions, manage the needs and moods of their crew, encounter other space-faring groups, and explore the universe in this spaceship colony simulation.

The Last Starship is a 2D space construction game where you design and upgrade your starship. Choose your path: pirate hunter, miner, engineer, spacebus driver, and more, whilst exploring vibrant star systems. Enjoy a growing sandbox world, with regular free updates. Your cosmic adventure awaits!

Fortress Fury is a survivor multiplayer tower defense roguelite. Endless hordes of enemies want to crush your tower! Buy weapons and upgrades to craft an array of overpowering builds. Will you be able to survive all waves and be the last tower?

Eden Crafters is a solo or co-op open-world survival, crafting, and factory-building game where you transform a hostile planet into a habitable haven for humanity. Build, automate, and terraform. Control the climate, create a breathable atmosphere, and turn toxic lakes into water: shape a new world!