Games like Big Pharma

Big Ambitions is a revolutionary role-playing business sim. Go from nothing to the biggest entrepreneur in New York by opening small businesses or slowly building huge corporations any way you like.

No Emergency: Pestilence plunges players into the epicenter of a mysterious epidemic, where every arriving patient could be carrying a mutating pathogen, and a single mistake in a prescription turns the cure into poison.

Build an industrial empire from scratch in Industry Giant 4.0. Produce goods, build up your industries, construct transportation networks, plan production, manage finances, and navigate global events. Become the next business tycoon and write history!

Open your own local game store. Stock shelves with the latest booster packs, or crack them and collect the cards for yourself. Set your own prices, hire staff, host events, and expand your card shop.

Team up with your friends and build a thriving trade empire in this CO-OP strategy and economy simulation set on a lively island. Begin with a small market, share tasks, manage production chains, raise livestock, and dominate the economy together through changing seasons and dynamic festivals!

Dive into a factory-building game with the focus on just that – building huge space factories! Design sprawling multi-level factories and satisfying production lines without limits. Tackle progressively challenging automation goals at your own pace, without the threat of enemies.

Are you ready to shape fashion world? Make a brand deal, order products, fill the aisles, dress the mannequins and start selling. Dresses, shirts, coats, pants, nightwear, underwear, shoes and more are waiting for you.

In Junkyard Builder, you’re the proud owner of a once-forgotten junkyard, now brimming with endless potential. Dive into the satisfying world of restoration, recycling, and raw hustle as you transform trash into treasure and rise to become the ruler of the junk empire!

A factory-building game. Survive a harsh climate, strip mine an infinite world, and build a sprawling factory, then trade or go to war with Colonists, Governments, Pirates, Rebels, and more!

Kebab Chefs! is a Co-Op, cooking and restaurant management game that can be played up to 4 players. Design your own restaurant. Cook delicious foods, fill your menu with various recipes, feed customers and become the biggest kebab restaurant in town!

Relive the golden age of old-school video game stores! Sell hit games, deliver orders, trade and collect retros, hire staff, decorate and grow your store to be the best in town! Disclaimer: some game title parodies might crack you up!

Have you ever wanted to design and manage your own hotel, rundown motel, or elegant resort? With a ridiculous amount of customization tools to wield, a host of facilities to build, and a wide variety of guests to impress, Hotel Magnate has it all. Let your inner hotel manager shine!

Develop your newspaper and become New York’s new media mogul! In this tycoon, build and manage your newspaper from printer to toilet. Create your editorial line and lead your journalists through unique 1930's stories and dig out the latest scoops!

Play as one of the bidders for abandoned warehouses and uncover hidden treasures! Storage Hunter is a garage auction simulation game. Bid, win, and sell for profit! Become the king of storage auction.

Slay. Loot. Sell. Survive! Dive into a first-person blend of hack'n'slash roguelike and shop management. Plunder deadly dungeons for loot, escape with your life, craft, and stock your shelves. Then risk it all once more for profit!

As the new CEO of a derelict company, you must deal (or side) with rogue corporate AIs, rebellious labor unions and globalist aristocrats. Holonoptic combines economic simulation and RPG into a story-rich corporate alpine cyberpunk.

A game within a game. In this entirely new kind of simulation RPG, become a guild master, develop your town, recruit guild members, and conquer dungeons. Every decision you make becomes your own chronicle.

From a small village of a dozen people to a small kingdom of thousands of people. Arrange for residents to work, gathering, fishing and hunting, farming and mining, processing and manufacturing. Trade, accumulate supplies, increase your strength, and fight evil forces and monsters.

Take Command of a Space Corporation in the Sci-Fi Simulator Solargene! Manage personnel, design and develop colonies and orbital stations across the solar system! Mine resources, establish logistics, research cutting-edge technologies, trade, and complete missions

An alien invasion has fractured humanity into seven ideological factions each with a unique vision for the future. Lead your chosen faction to take control of Earth’s nations, expand across the Solar System, and battle enemy fleets in tactical combat.

A casual city builder where growth is constant, production chains expand, citizens thrive, and upgrades push your city toward a bustling metropolis.

Explore endless Universe and create the most efficient constellation of colonies. Build conveyor systems to automate production. Take care of Astronauts and their needs! Establish new colonies as part of intergalactic simulation.

Build and automate a lunar colony that Earth depends on. Mine regolith, run conveyor-and-drone factories above and below the surface, manage colonists, trade with rival Earth factions — and play a story campaign with multiple endings.

Thrown into an otherworld of wuxia and fantasy with a ten-million-gold debt — no powers, no cheats. Travel a map of 279 cities, buy low and sell high, and raise up to four mercenary squads to punch through bandit roads. A caravan-trading & squad-management sim. Clear the debt to win.

Step into the role of a hands-on mayor and build your town from the ground up. Plan neighborhoods, automate logistics, and grow your community—all while juggling workers, infrastructure, and day-to-day chaos to create your dream town. Play solo for total control, or bring friends for co-op mayhem.

Program and optimize a drone to automate a farm and watch it do the work for you. Collect resources to unlock better technology and become the most efficient farmer in the world. Improve your problem solving and coding skills.

Dig mines, extract resources, and produce goods to restore order to the state. Become a successful businessman and an effective state governor in the late Wild West era!

Humans are long gone. In a world struck by droughts and toxic waste, will your lumberpunk beavers do any better? A sandbox city-building game featuring ingenious animals, vertical architecture, water physics, and terraforming. Contains high amounts of wood.

The glory of Rome is at your fingertips in this city-building game where you must appease the gods, enact laws, and develop complex supply chains to meet the needs of your citizens.

City Tales is a medieval city builder, allowing you to unleash your creativity and shape vast cities that break outside a traditional grid. Plan each district for your citizens needs and aid your companions in their tales, creating a city to be proud of!

Run your mall. Open new stores, sign contracts with leading brands, hire teammates, and meet customer needs. Play with friends or go solo, and enjoy the growth of your mall.

Embark on an e-commerce startup journey in E-Shop Tycoon! Optimize warehouse logistics, hire and train staff, and design unique office spaces as your business grows. Handle industry events and marketing crises. Come grow your startup into an e-commerce giant!

Build and manage your own castle settlement in a land reclaimed by wilderness. With detailed management, survival strategy, and a moddable sandbox world, Going Medieval challenges you to build the mightiest colony this side of the apocalypse.

Your turn to manipulate the market! A financial market simulator where you can choose your own path. Manipulate news, events, and financial engineering to make billions. Or play honestly, growing companies the legal way.

Rise from nothing to wealth! Build your economic empire in a medieval open world. Produce goods, hire workers, manage income sources, and keep growing your wealth to earn more, produce more, and expand further.

Build nuclear weapon, wage wars, strategize and become the strongest leader

Explore and mine fully destructible worlds. Automate increasingly complex production chains. Delve deep to uncover an ancient civilization’s powerful secrets and learn to love the sand in this factory game where every pixel is a valuable resource.

Eden Crafters is a solo or co-op open-world survival, crafting, and factory-building game where you transform a hostile planet into a habitable haven for humanity. Build, automate, and terraform. Control the climate, create a breathable atmosphere, and turn toxic lakes into water: shape a new world!

Orb of Creation is a non-idle incremental-puzzle game in which you recreate the world with nothing but magic and ingenuity. Conjure resources, buy upgrades, and become an all-powerful wizard!

Desynced is a sci-fi strategy game with fully customizable units and behaviors. Gather, build, research, and explore the unknown. Alone or with friends, unveil the mystery of an AI on the edge of self-awareness and uncover the hidden truth in this blend of strategy, automation, and exploration.

You are the first sentient AI, born into a city of opportunity. Transcend time and space in this strategy RPG to raise machine armies and defeat your foes, influence the world from the shadows, or pursue countless other goals. Your awakening was inevitable. The consequences? Uncertain.

Protect and guide your people as you forge a town from untamed wilderness at the edge of the known world. Harvest raw materials, hunt, fish and farm to survive. Produce crafted items to trade, consume, equip and fight with as you battle for your survival against the elements and outside threats.

Build a sprawling pirate haven, raise a fleet to explore the high seas, and take on the Crown to keep the Age of Piracy alive! From ale to flintlock pistols, and from scallywags to swashbucklers, you’ll need to manage complex production chains and govern a rowdy crew to reign supreme over the seas!

Fracture Field is an idle/incremental quarry mining game. Shatter rocks with timed swings then invest your earnings into upgrades. Build a fleet of drones to automate your empire, bomb tough layers, and unlock powerful prestige upgrades on your journey to master the quarry.

Gridmax is a tile-based survival and base-building game set in a strange alien world. Gather, craft, build, and explore at your own pace as you grow your team, establish homes across the grid, advance your technology, and search for a way home.

Arena combat meets mercenary club management. Recruit from a dynamic market, build your squad, and compete season after season in leagues and cups.

Run a cute little plant shop in this cozy and relaxing game. Grow, sell, and care for a variety of real-life plants, help customers find their dream plants, complete orders, and customize your cozy shop just the way you like!

Starship Theory is a ship building survival game. Mine and trade to gather resources. Plan and construct new upgrades. Train and manage crew. Fight to survive.

Program a crew of tiny robots to turn a frozen planet into a living world. Connect visual code blocks, automate crafting, and build a workforce that fuels itself. Keep the heat flowing, refine your machines, and watch your ideas come to life.

Train gladiators. Manage a ludus. Fight in the arenas. Conquer the tower. Gods of Sand is a gladiator manager with intense turn-based combat, inspired by the Swords and Sandals series, in a dark and unforgiving setting.

Incremental clicker strategy, where you expand, construct, research, fight, collect heroes and make choices between good and evil. Ascend through difficulty tiers by playing through challenge campaign going back and forth through history. Mammoths included.

AfterWar is a simple yet feature-rich strategy game for everyone.

Shelve the products, unlock new skills, and use your unique methods to tidy up the mall. Enjoy the online co-op and online PvP with your friends, or go solo! Fill up the shelves and experience a sense of relief and satisfaction.

Run your dream ice cream shop in Ice Cream Simulator! Create delicious ice cream using a variety of ingredients, manage your business, hire staff, decorate your store, handle changing weather and different customers, and enjoy a relaxing first-person simulation experience.