Games like Substrate: Emergence

Be the architect of your own universe with Spore, an exciting single-player adventure. From Single Cell to Galactic God, evolve your creature in a universe of your own creations.

Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.

Create virtual lifeforms whose development is shaped by a deep simulation of evolution. Guide them as they fight, mate, and adapt to the environment you have built. All the creatures in the trailer evolved on their own in the game!

The Sapling is a simulation game where you design your own plants, animals, algae and fungi, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!

WorldBox is the ULTIMATE god simulator and sandbox game. A petri dish for your fantasy civilizations. Create your own world or destroy it using many powers. Watch civilizations grow, form kingdoms, colonize new lands, sail to far continents, wars to ignite, empires to fall and towns to burn!

Play a major role in an evolving simulation of simulations. Explore endless 2D and 3D dimensions spanning nearly every game genre, with 50+ experimental prototypes and stories whose worlds, systems, discoveries, and ideas can become part of the greater experience.

Become a God, build a civilization. In this dynamic Roguelite God Simulator, guide human civilization on a procedurally generated pixel world. Watch your people grow, defend them against heretics, and build an immortal legacy.

Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.

Jump straight into managing your own planets as you guide a civilization through the ages. Build the ultimate empire in The Universim, a new breed of God Game in development by Crytivo.

Experience a mystical journey with the Mims in this strategic god-like adventure—build, grow, protect, and wield divine powers. Now it's completely free! Also check out our other story-rich fantasy game, The End of the Sun, where you become a tracker of mythical beings and unravel mysteries.

Legendary creature is an independent game with rich playing methods such as roguelike + self-propelled chess + strategy. You can collect all kinds of magic creatures with various talents and skills, and can also evolve to a higher level.

Play with friends in a cozy base-building adventure! Take care of adorable creatures — Morps, explore, discover new species, grow crops, fish, build relationships with your crew, decorate your perfect home, and automate production along the way!

Live the experience of being a powerful god and create the world to see the growth of mankind.

A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.

Oxygen Not Included is a space-colony simulation game. Deep inside an alien space rock your industrious crew will need to master science, overcome strange new lifeforms, and harness incredible space tech to survive, and possibly, thrive.

Build a fortress and try to help your dwarves survive against a deeply generated world. Keep your dwarves happy, grow their community and beware of digging too deeply. The deepest, most intricate simulation of a world that's ever been created.

Start your own cult in a land of false prophets, venturing out into diverse and mysterious regions to build a loyal community of woodland Followers and spread your Word to become the one true cult.

Command swarms of warriors at an unprecedented scale of warfare in this blend of RTS and base-building. Lead ant colonies against the many fearsome threats of the insect world, while building intricate nests, developing pheromone-based tactics, and evolving to meet growing dangers.