Games like Protolife

Defend humanity's last hope, pilot a powerful mech, in Frontlines Crisis! A battlefield swarming with insects makes strategic and combat decisions crucial. Each decision will determine your fate. Defend humanity's last sanctuary, fight fiercely, and uphold human honor with wits and courage!

Build and design the terrain while defending your stronghold against alien invasion in this unique Roguelike tower defense. Choose from 30 heroes, survive enemy waves, and upgrade a variety of destructive towers to hold the line!

From Glory To Goo is a Sci-Fi survival RTS set on an alien world. Serve as humanity's bulwark by establishing a colony and supporting your colonists still in orbit. But beware, for The Goo, a relentless and shape-shifting force approaches from all sides, even above and below.

Age of Darkness: Final Stand is a dark fantasy survival RTS where you must illuminate, build and defend humanity’s last bastion against hordes of Nightmares. Set in the remnants of a kingdom consumed by a deadly fog, you decide. Will you hide in the light? Or take back your world.

Tower Factory is a tower defense and automation game with roguelite elements. Optimize resource production using conveyor systems while defending against monster waves. Can you find and destroy the enemy tower before it's too late?

Collect resources and establish a defense line before dark And then Facing countless enemies

A defense RTS where you can move turrets at will. Extract resources, upgrade technology, and defend against enemy swarms in a gripping space campaign. Hold the line, set up your turrets, and brace for screen-filling hordes!

As the kingdom's most promising pioneer, embark on a legendary journey to tame the frontier! Build thriving towns across various landscapes, fending off waves of diverse enemies until you establish a firm foothold and have explored everything the eye can see!

Stellar Initiative is a roguelike tower defense game where you land on the planet and use your orbit ship to deliver buildings and support you with fire. Complete missions, install new upgrades, discover powerful artifacts, and find the best strategy!

Stormgate is a free-to-play real-time strategy game with a full single-player campaign, 3-player co-op, and PvP versus modes on over 60 maps. Our Editor is also freely available for you to craft just about any custom game mode you can imagine. Join our development journey today!

Build twisting mazes with tetromino blocks and deploy unique towers in this strategic roguelite tower defense adventure!

Are you prepared for a thrilling toy army tower defense adventure? Welcome to the Toy Shire! Battle diverse foes in various locations, defend your family, and repel foes from your area. Save the world by strengthening your defense with toy towers!

clickyland is a tower defense village builder where clicks are your main resource. Use clicks to harvest resources, fight enemies and manage your village, but use them wisely as you only get 20 clicks every day! Can you reach day 100?

The RTS/FPS phenomenon has moved into space! Build your base on an asteroid, command fleets of starships for epic battles, pilot fighters, mine and trade resources, assemble robots to defend or assault other stations. Take sole command or share the glory as you fight for control of the quadrant.

Axon TD lets you expand the map boundaries themselves. A huge arsenal of towers and a wide variety of enemies clash in a battlefield that grows to your whims. Engage in single, cooperative, and roguelite gameplay.

Command Mobile Outpost and take XEN Firearm to venture deep into the Signet surveillance off-limit area. Collect unique Weapon Units. Amp up the firepower of the Outpost that fights with you. This is an FTD game - FPS, Tower Defense, Base Building and much more all at the same time.

Hexguardian is a roguelite, tower defense game where you build your own maps with hexagonal tiles! Build and upgrade towers, recruit armies, learn spells, construct wonders and place hexagonal tiles to create a path to enhance your defenses. With plenty of game modes and talents to unlock!

Cluckmech Oasis, a top-down shooting Roguelike tower defense game. Play as the Warcluck and lead your team of animal heroes in a fight for survival. Collect, build and upgrade defenses, and engage in intense battle against waves of plant enemies.

A minimalist game about building and defending your little kingdom.

Hard-core action with easy controls! The METAL SLUG we all love is back as a tower defense game!

In ShapeHero Factory, you’re the engineer of an ever-evolving paint-fuelled factory that spits out magical, shape-based warriors. Send them into battle - to death or glory - then build an even better factory on your next run.

The unstoppable alien force known as The Creeper has returned, devouring thousands of worlds in its path, and yours is next. Battle against the Creeper fluid in a groundbreaking pixel-level simulation to prove that humanity will rule the galaxy forever!

The Front is a survival open-world crafting sandbox game. You are a resistance fighter sent back in time to stop the rise of a tyrannical empire. Collect resources, craft tech, build shelters, and fight monsters to accomplish your mission.

Enemies are coming! Every decision matters: build your city, grow the economy, and prepare for enemy waves. Strengthen your defenses, adapt your strategy, and unleash your hero’s full potential. This unique Tower Defense will test your skills – are you worthy to claim a place at Valhalla?

Unleash voxel warfare in 9-Bit Armies: A Bit Too Far. Lead a modern military, build bases, unlock units, and attack in all-out war. Engage on land, sea and air in over two dozen missions, online skirmishes, or co-op. Easy to learn, a challenge to master.

Critter Chaos TD is a fast, frantic and chaotic Tower Defence game in which you must rid the world of the evil Critters. Build stations and guns to fortify your defences and prevent the various types of Critters from reaching your base.

Command distinct factions in a desperate struggle for power and resources in Tempest Rising - a classic RTS set on Earth after a nuclear war.

Mineral Defense combines tower defense with roguelite elements and procedural generation. Build paths, unlock upgrades, and unleash powerful synergies to conquer evolving challenges in an ever-expanding world.

Diplomacy is Not an Option is a strategy game set in a medieval fantasy world. Build your town and defenses, raise huge armies and fight against massive hordes of enemies. How long can you survive?

2D Strategy game.

Tactical, beautiful, and wholly unique, the GOTY-winning sci-fi RTS returns with Homeworld 3. Assume control and battle through fleet combat in dazzling, fully 3D space while the award-winning story unfolds on a galactic scale.

Build a castle by day and defend it by night. Becastled blends cozy city-building with challenging tower defense strategy. Lead the Sun Kingdom’s last stand against the Moon Beasts and end the ancient conflict between light and darkness!

Create a thriving space station in a lost sector. Face thrilling challenges head-on, from pirate raids to asteroid impacts, as you lead your company to new heights.

Artisan TD is a puzzle-oriented Tower Defense game where you must survive by building mazes.

Desynced is a sci-fi strategy game with fully customizable units and behaviors. Gather, build, research, and explore the unknown. Alone or with friends, unveil the mystery of an AI on the edge of self-awareness and uncover the hidden truth in this blend of strategy, automation, and exploration.

SENTRY is an action-defense first person shooter where you defend your spaceship against invading aliens. Plot an escape route through hostile space and battle the enemy across your vessel with the support of traps, turrets and environmental destruction.