Games like Defend Your Life: TD
by Alda Games
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.
View on Steam · $9.99 →
Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
$4.99Operation: Outbreak Idle
Sep 4 · DeadLogics
Both: Tower Defense
Command automated military defenses, upgrade your fortress, and survive massive zombie waves in this action-packed idle defense game. Build powerful defenses, unlock upgrades, and hold the line against endless undead hordes.
Tower DefenseZombiesStrategySingleplayerCasualSurvivalShoot 'Em UpIncrementalShooter3D
$4.99Kingdom Contracts Tower Defense Incremental
Aug 14 · Day 1 to 100
Both: Tower Defense
You are the Kingdom’s Commander. Choose new contracts strategically. Use towers but save your gold. Use 12 powerful God/saint spells. Finish Contracts quickly. Stack gold and reputation rapidly. Choose and upgrade 36 perks blessed by 12 Gods/saints. Become the Legend of the Kingdoms.
Tower DefenseMinimalistStrategyRogueliteRelaxingSingleplayerAtmosphericCasualIndie3D
$1.99Critter Chaos TD
Oct 31 · Chaos Creations
Both: Tower Defense · RTS
Critter Chaos TD is a fast, frantic and chaotic Tower Defence game in which you must rid the world of the evil Critters. Build stations and guns to fortify your defences and prevent the various types of Critters from reaching your base.
StrategyAction RTSWargameTower DefenseRTSEarly AccessCasualActionIndieBase Building
FreeFortress Fury
Jan 21 · Kervado
Both: Tower Defense
Fortress Fury is a survivor multiplayer tower defense roguelite. Endless hordes of enemies want to crush your tower! Buy weapons and upgrades to craft an array of overpowering builds. Will you be able to survive all waves and be the last tower?
StrategyActionTower DefenseBullet HellRoguelite2DTop-DownCuteColorfulMagic
-15%$1.69Card Shelter Defence
4 days ago · NeographGamer
Both: Tower Defense
Recruit cards, assign them to shelters, and stop incoming waves in a strategic tower defense game. Combine three cards to strengthen your forces, manage limited resources, and adapt to each scenario.
StrategyTower Defense2DSingleplayerCard BattlerFamily FriendlyResource ManagementIndie
-15%$8.49Crown Siege
3 days ago · JOrbits Games
Both: Tower Defense
A short incremental siege game centered around growing and strengthening an army to defend your kingdom. Seize the crown from an endless wave of enemies for your best chance at survival!
IncrementalAuto BattlerTower DefenseCasualIdlerActionHack and SlashMedievalSimulationStrategy
-15%$4.24Demonic Defense
4 days ago · xHo
Both: Tower Defense
Guard your campfire through the night and feed your rivals' rifts with monsters. A multiplayer tower-defense survival hybrid where deck building, base building, and dueling economies decide who survives and who freezes.
Early AccessCard BattlerTower DefenseReal Time TacticsAction RoguelikeTrading Card GamePvEPvPStrategyTutorial
$19.99Repterra
Aug 20 · Chute Apps
Both: Tower Defense · RTS
Repterra is a base-building survival RTS set in a world overrun by dinosaurs. Manage your colony while battling massive dino hordes. Breed and ride your own dinos, unlock permanent upgrades, and fight to reclaim the world for humanity.
Real-Time with PauseBase BuildingDinosaursTower DefenseRTSCity BuilderStrategyPvEResource ManagementIsometric👍 122
$19.99The Front
Oct 30 · Samar Studio
Both: Tower Defense
The Front is a survival open-world crafting sandbox game. You are a resistance fighter sent back in time to stop the rise of a tyrannical empire. Collect resources, craft tech, build shelters, and fight monsters to accomplish your mission.
Open World Survival CraftMultiplayerSurvivalCraftingBase BuildingBuildingOpen WorldTower DefenseSandboxShooter👍 9,553
$6.99Claws of Power
Aug 21 · 蒜苗
Both: Tower Defense
Claws of Power is a cute, real-time card battle game. With a variety of unique and adorable cat cards, each one could be your key to victory. Strategize by building different decks and using items to overcome challenges and claim the throne as the ultimate cat leader.
Tower DefenseCard BattlerHand-drawnCatsReal Time TacticsCuteCasualCard Game2DRelaxing👍 170
$2.50OmniSeed
Jul 13 · Velest
Both: Tower Defense
Play as a kind-hearted god in a tiny world. Grow thriving forests, inspire mortals to stand strong, and unleash nature's fury to shield them from evil. One small miracle at a time.
RogueliteTower DefenseGod GameDeckbuildingCard BattlerTacticalPixel Graphics2DTop-DownSingleplayer
$19.99Becastled
Oct 22 · Mana Potion Studios
Both: RTS
Build a castle by day and defend it by night. Becastled blends cozy city-building with challenging tower defense strategy. Lead the Sun Kingdom’s last stand against the Moon Beasts and end the ancient conflict between light and darkness!
Base BuildingStrategyCity BuilderMedievalBuildingRTSColony SimWarMilitarySingleplayer👍 5,352
FreeThe Perfect Tower II
Nov 30 · Fire Sword Studios
Both: Tower Defense
The Perfect Tower II is a mix between an incremental and a tower defense game. Build a town, manage resources and explore a variety of mini-games and tons of upgrades. Fully automate your game and watch numbers going up!
Tower DefenseIdlerStrategyAutomationResource ManagementActionMinigamesVoxelBase BuildingIncremental
$3.99Last Hope: Zombie Autobattler
Jul 27 · Hands-Off Games
Both: Tower Defense
Build your towers and let them do the killing! Connect 12 unique towers through the Reactor to discover 144 devastating synergies. Kill endless zombie hordes, mutate them for bigger rewards, and push your build to the limit in a chaotic bullet hell.
Tower DefenseIdlerZombiesBullet HeavenRogueliteRoguelikeResource ManagementSurvivalPost-apocalypticStrategy
-43%$11.39Survival Machine
Jun 12 · Grape Pickers
Both: Tower Defense
Build your base on a moving Machine, travel through biomes with different resources, and prepare for the night when a zombie threat is much higher than during the day. Would you go solo or explore this new world with your best friends?
StrategyTower DefenseBase BuildingOnline Co-OpZombiesResource ManagementCraftingCombatExplorationThird Person👍 692
$1.00Dealer's Dice
Sep 7 · OFFMOON Inc.
Both: Tower Defense
Trapped in the twisted game room of a mysterious entity, Dealer's Dice is a high-stakes roguelike dice-defense game. Collect powerful dice, manage your betting table, and gamble against relentless waves of invaders. Push your luck, test your greed, and survive.
Tower DefenseIncrementalCasualDiceRoguelikeRogueliteStrategyChoices MatterIndieArcade
Also worth a look
Share some of the same DNA, but further from the original.
-25%$11.24There Is mORE
4 days ago · ByteBeyond
Both: Tower Defense
Mine by day, defend by night. Master 25+ spells, sell rare ores for gear upgrades, and grow stronger each run in this procedurally generated roguelite tower defense. Enjoy full controller and Steam Deck support.
RogueliteTower DefenseAction RoguelikeMiningSurvivalProcedural GenerationExplorationMagicBase Building2D
$2.99Last Bastion Protocol
12 days ago · mr_pancake
Both: Tower Defense
Defend the last evacuation corridors in a tactical tower defense game. Build and upgrade specialized towers, counter varied machine threats, and withstand HECATE's forces across the campaign, Siege, Skirmish, and Endless modes.
StrategyTower DefensePvEIndieAbstractDystopian Level EditorAtmosphericSingleplayerCasual
$9.99Runeomicon
5 days ago · TLR Games
Both: Tower Defense
Perform a dark ritual with your own hands under relentless pressure. Draw runes in real time, defend the ritual from enemies trying to stop it, and upgrade your skills to unleash devastating magic. Summon ancient eldritch gods in this dark fantasy game driven by skill, strategy and constant tension.
Tower DefenseResource ManagementReal Time TacticsStrategyPixel GraphicsSide Scroller2DActionDifficultDark Fantasy
$17.99Dying Breed
Oct 7 · Sarnayer
Both: RTS
Golden-age RTS classic. Fast-paced action & strategic decision-making, battling evil arch-enemies, zombies, and retro-futuristic technologies. All to a '90s electro-metal soundtrack and FMV live-action cut scenes.
Early AccessStrategySingleplayerRTSBase BuildingTacticalActionWarPost-apocalypticSci-fi👍 218
$10.99Sineus Arena Survivors
Jun 22 · Sineus Games
Both: Tower Defense
Fight hordes and defend your Stronghold in a bullet heaven survivor-like with co-op and tower defense. Gain power-ups every level, collect random artifacts from chests and grow stronger to survive, defeat the boss and claim a top spot on the Sineus Arena leaderboards!
Bullet HeavenAction RoguelikeRoguelikeOnline Co-OpCo-opBullet HellLootTower DefenseScore AttackIndie👍 1,163
$3.99CoreBreaker: Desktop Swarm
Jul 15 · Furistic
Both: Tower Defense
A corner screen incremental brick-breaker where bouncing cores destroy endless swarms. Let it run in the corner of your screen while you work or jump into fullscreen and take control yourself. Unlock new Cores, expand your skill tree, survive endless waves.
Desktop CompanionAuto BattlerIdlerIncrementalCasualStrategyRoguelikeBullet HeavenTower DefenseRoguelite
$14.99Yet Another Zombie Survivors
Aug 20 · Awesome Games Studio
The Horde is coming, but you're ready to fight it! Assemble your squad, choose their upgrades, and build powerful synergies against thousands of undead. Survive. Then evolve. Then break every limit in this deceptively simple but addictive bullet heaven game.
Bullet HeavenAction RoguelikeZombiesTop-Down ShooterRogueliteIndieArcadeSingleplayerAction RPGRoguelike👍 14,162
FreeGods and Kings
Jun 27 · DragonNest
Both: RTS · Tower Defense
A game that combines real-time strategy, card collection and role-playing. It's based on Greek mythology. You can play as heroes who can manipulate the power of Rune, summon the army and cast magic to defeat enemies, challenge or defend the authority of the Gods.
Free to PlayRPGStrategyTacticalEarly AccessViolentRTSCard GameTower DefenseHack and Slash
$14.99Territory: Farming and Warfare
Feb 4 · Wit Studio
From a small village of a dozen people to a small kingdom of thousands of people. Arrange for residents to work, gathering, fishing and hunting, farming and mining, processing and manufacturing. Trade, accumulate supplies, increase your strength, and fight evil forces and monsters.
SingleplayerSimulationBase BuildingCity BuilderStrategySandboxAutomationPixel GraphicsResource ManagementBuilding👍 738
$12.99The Spell Brigade
Apr 29 · Bolt Blaster Games
Survivors-like with ONLINE CO-OP for 1-4 players. Team up with your wizard friends to slay hordes of dark creatures. Complete team-based objectives, unlock new upgrades and create overpowered spell synergies. Friend nor foe is safe in this friendly fire bullet hell!
Bullet HeavenOnline Co-OpRogueliteBullet HellCo-opAction RoguelikeRoguelikeMagicMultiplayerAction👍 14,750
-15%$3.39Tower Realm
Aug 11 · Charge Piggy Studio , Kitchen Group
Both: Puzzle
Tower Realm is a high-strategy Magic Tower RPG collection with fixed maps and stats, auto turn-based battles, and precise resource-route planning. Clear hardcore with no supplies, or use the Green Key to lower difficulty. Earn clear points to unlock custom challenges.
AdventureStrategyRPGPuzzleJRPGBoard Game2D PlatformerTurn-Based TacticsDungeon Crawler2D👍 110
$5.99Cultivation Road
Aug 19 · Fengling Studio
Both: Tower Defense
"Cultivation Tower" 2.0 "Cultivation Road", 2D side-scrolling idle cultivation game. Lead the protagonist and 12 fellow cultivators on an automatic journey along the immortal path, battling and collecting treasures, managing your sect, constantly reaching new heights in twenty different scenes.
CasualStrategyRPGTower DefenseAuto Battler2D PlatformerIncrementalIdler2DAnime
$9.99Pathogenic
Jul 16 · Aberrant Labs
You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions.
RoguelikeBullet HellTop-Down ShooterLocal Co-OpBullet HeavenAction RoguelikeDifficultDungeon CrawlerShooterCharacter Customization👍 4,186
$69.99Echoes of Aincrad
Jul 9 · Game Studio Inc.
Step into Aincrad, a world of beauty and danger where every battle could be your last. Create your hero, choose your gear, and master combat by building synergy with your partner, leveling up, and unlocking special abilities to expand your horizons.
AnimeSingleplayerJRPGAction RPGSouls-likeFantasyHack and Slash3DRPGCharacter Customization👍 4,115
-20%$7.19Save Mom
3 days ago · Amigos Entertainment
Both: Cartoony · Funny
A co-op action game about protecting your mom in a post-apocalyptic world. Explore ruined cities, gather resources, upgrade your motorhome, build defenses, and battle enemies. Your mission: Get Mom to safety. Her survival is in your hands!
ActionCo-opCartoonyTop-Down ShooterPvEFunnyShooter3DPost-apocalypticBase Building
$29.99Going Medieval
Mar 17 · Foxy Voxel
Build and manage your own castle settlement in a land reclaimed by wilderness. With detailed management, survival strategy, and a moddable sandbox world, Going Medieval challenges you to build the mightiest colony this side of the apocalypse.
Colony SimBase BuildingStrategyVoxelSurvivalManagementCity BuilderSingleplayerSandboxNature👍 17,036
$14.99Lucky Tower Ultimate
Apr 16 · Studio Seufz
Escape from an incredibly dangerous, randomly generated tower in a slapstick, roguelite adventure that looks like a cartoon and feels like a joke. Slashy slashy!
Action RoguelikeDungeon CrawlerProcedural GenerationAdventureDark HumorDifficult2DCartoonHand-drawnComedy👍 2,282
$9.99ZENONIA 1
Aug 31 · Com2us Holdings, CFK Co., Ltd.
Both: Cartoony
Remember the RPG that defined a generation? ZENONIA is back—faithfully restored and now on Steam. Relive the adventure that kept you playing for hours, or experience it for the first time.
RPGAction RPGIndieAdventure2DAction-AdventureCuteCartoonyPixel GraphicsFantasy👍 440
$17.99Kebab Chefs! - Restaurant Simulator
Jun 11 · Biotech Gameworks
Both: Funny
Kebab Chefs! is a Co-Op, cooking and restaurant management game that can be played up to 4 players. Design your own restaurant. Cook delicious foods, fill your menu with various recipes, feed customers and become the biggest kebab restaurant in town!
CookingMultiplayerSimulationManagementPhysicsSandboxFunnyTime ManagementImmersive SimBuilding👍 7,017
-35%$9.74Dwarves: Glory, Death and Loot
Jan 22 · Hamma Studios
Build and command your own party of Dwarves in a chaotic mix of Auto Battler, Strategy, and RPG. Prepare formations, assign equipment, and decide the fate of up to 10 Beardlings, as you lead the raid party through reckless runs filled with Glory, Death, and Loot!
Auto BattlerDwarvesRPGRoguelikeCharacter CustomizationStrategyLootParty-Based RPGTactical RPGPerma Death👍 2,591
$19.99Screeps: Arena
Nov 1 · Screeps, LLC
Both: RTS
Screeps: Arena is an online asynchronous PvP strategy game for programming enthusiasts. You write real JavaScript to control your units, and they fight autonomously against other players in a 1v1 match-based arena environment.
StrategyAsynchronous MultiplayerPvPArtificial IntelligenceRTSTurn-Based TacticsAutomationeSportsReal Time TacticsSimulation👍 105
$7.99BOMBANANA!
Sep 2 · Lefto Studio
Both: Puzzle · Funny
Chaotic bomb disposal fun with friends & monkeys! Work together as a 3-player co-op team of blind, deaf, and mute monkeys. Each player has only part of the needed information. Communicate, solve puzzles, and race against the clock. Can you defuse the bombs before they explode?
MultiplayerTeam-BasedOnline Co-OpPuzzleParty GameCasualComedyTime ManagementIndieFunny👍 2,476
-20%$15.99Rubinite
Jul 22 · Cup Dog Games, GameWorks Ventures
Rubinite is an extremely challenging boss rush action game. in a dark fairy tale world, use Ruby's crimson eyes to expose the weak points of the Bloodstained monsters, then strike and shatter them. Carve a road home through the ruined Scarlet Kingdom and face the Witch who took it all.
DifficultPixel GraphicsBoss RushSouls-likeFemale ProtagonistIndie2DAction RPGTop-DownAction👍 3,626
-15%$6.79Bullet Train
4 days ago · mis.hinged
Both: Cartoony
Welcome on the Bullet Train: destroy enemy towers, collect powerful orbs and improve your train! Fight through escalating enemy territory to defeat the creatures that destroyed your town!
Vehicular Combat3DActionAction RoguelikeIndieMemesFantasyCartoonySingleplayerDragons
$3.99小白人極彩決戰
Nov 12 · KongshiStudio
Little White: Chromatic Clash is an action-packed boss battle game where players face a variety of uniquely designed bosses. Challenge each boss to the fullest and aim for the highest score possible!
ActionAction-AdventurePlatformer2D PlatformerPixel GraphicsHack and SlashEarly AccessSingleplayer
$14.99Rising Front
Jan 9 · Sandstorm Studios Inc.
A FPS WW1 & Revolutionary War battle simulator with a focus on Workshop Content, rag-doll physics, intelligent AI, massive battles, procedural AI cover system, real-time building system and FPS combat!
SandboxWarSingleplayerWorld War IFPSSimulationActionShooterStrategyHistorical👍 4,062
-30%$6.99MIMESIS
Oct 27 · ReLU Games, Inc.
Both: Funny
A 4-player online co-op survival horror game. Avoid the contaminated rain, gather scrap and get back to the tram. Monsters that copy your friends' voices and behavior, and many other threats, stand in your way. Gear up and stick together to survive.
Early AccessOnline Co-OpSocial DeductionPsychological HorrorFunnyPvEPost-apocalypticExplorationRogueliteSurvival Horror👍 8,404
$19.99Hot Dogs, Horseshoes & Hand Grenades
Jul 4 · RUST LTD.
Both: Funny
Do you like hot dogs? How about horseshoes? Hand grenades? (everyone likes hand grenades) Anyway, we've got all that, and guns. SO MANY GUNS. So if you like ordnance, meat, and far too many groan-worthy puns, this is the VR sandbox game for you.
SandboxVRShooterPhysicsFPSSimulationGun CustomizationFirst-PersonFunnyModdable👍 22,782
-50%$4.99Asgard's Fall — Viking Survivors
12 days ago · Soulpotion
Embark on an epic saga in Asgard's Fall, a norse Survivors-like Roguelite. Fight your way through hordes of creatures and let the gods feel your relentless wrath. How will your saga unfold?
Action RoguelikeBullet HellRogueliteCasualPixel GraphicsIndie2DRoguelikeHack and SlashStrategy👍 1,305
$14.99Die in the Dungeon
May 1 · ATICO
Fight your way through a mysterious dungeon in this deck-building, turn-based roguelike game where you don't use cards, but dice! Deal with enemies by combining powerful dice on your board, boost their effects with magical relics, and risk it all hoping for a good roll on unexpected encounters.
RoguelikeStrategyDeckbuildingCard GameRoguelike DeckbuilderTurn-Based CombatCard BattlerIndieDungeon CrawlerRoguelite👍 3,240







