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Games like Master of Mutations

by Jigsaw Unravel

Master of Mutations is a 2D sci-fi strategy puzzle: matching objects to evolve zombies, managing chaos scales and placing objects on a grid. Zombie Night Terror and SpaceChem play most like Master of Mutations. Of the 12 closest games below, most share its puzzle and logic.

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Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.

Closest matches

Zombie Night Terror
Jul 20, 2016 · NoClip
Both: Zombies · Puzzle
Side-view 2D post-apocalyptic strategy puzzle action, pixel graphics. Command a zombie horde, solve puzzles and mutate zombies.
ZombiesStrategyPixel GraphicsIndiePuzzleActionLemmingsHorror2DGore👍 3,351
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SpaceChem
Mar 2, 2011 · Zachtronics
Both: Puzzle · Logic
Isometric 2D sci-fi design-based puzzle, detailed technical illustration. Constructing factories, transforming raw materials and solving puzzles.
PuzzleDifficultProgrammingIndieLogicSingleplayerAutomationSci-fiGreat SoundtrackScience👍 2,630
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Opus Magnum
Dec 7, 2017 · Zachtronics
Both: Puzzle · Logic
Isometric 2D fantasy open-ended puzzle game, steampunk alchemical. Designing machines, building alchemical processes and solving puzzles.
PuzzleProgrammingAutomationIndieSimulationLogicSingleplayerSteampunkGreat SoundtrackDifficult👍 5,998
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EXAPUNKS
Oct 22, 2018 · Zachtronics
Both: Puzzle · Logic
Isometric 3D sci-fi programming puzzle game, retro cyberpunk aesthetic. Programming viruses, hacking networks and automating tasks.
ProgrammingPuzzleHackingAutomationIndieSimulationLogicCyberpunkSingleplayerDifficult👍 1,380
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MOLEK-SYNTEZ
Nov 19, 2019 · Zachtronics
Both: Puzzle · Logic
2D sci-fi programming puzzle simulation, minimalist monochrome UI. Programming molecular synthesizers, optimizing chemical solutions and playing solitaire.
SimulationPuzzleProgrammingIndieSingleplayerScienceAutomationLogic👍 523
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The Signal State
Sep 23, 2021 · Reckoner Industries
Both: Puzzle · Logic
2D sci-fi puzzle automation programming, realistic electronic hardware. Solving puzzles, patching cables and programming logic.
PuzzleLogicSimulationAutomationProgrammingIndieSandboxLevel EditorModdableTutorial👍 653
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I, Zombie
Dec 8, 2014 · Awesome Games Studio
Both: Puzzle
Top-down 2D strategy zombie game, cute cartoonish. Commanding a zombie horde, infecting humans and tactical planning.
StealthTop-DownPuzzleLevel EditorCuteVillain ProtagonistCasualIndieStrategyArcade👍 2,179
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Once Upon A Death
Jul 26, 2019 · Gamenesis
Both: Zombies · Hand-drawn
Top-down 2D fantasy strategy adventure. Raise an army, raid and loot, collect resources.
IndieStrategyZombies2DSingleplayerHand-drawnDark FantasyFantasyComedyAdventure
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Bacteria
Mar 23, 2016 · Sometimes You
Both: Puzzle
2D puzzle, pixel art. Adding cells and creating patterns.
CasualIndiePuzzle👍 119
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while True: learn()
Jan 17, 2019 · Luden.io
Both: Puzzle · Logic
2D modern-day puzzle simulation, flat vector illustration. Building flowcharts, sorting data and managing freelance jobs.
ProgrammingEducationSimulationPuzzleIndieScienceBuildingSandboxCatsLogic👍 7,372
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SHENZHEN I/O
Nov 17, 2016 · Zachtronics
Both: Puzzle · Logic
2D modern-day programming puzzle simulation, technical digital interface. Building circuits, writing assembly code and engineering devices.
ProgrammingAutomationPuzzleLogicSimulationDifficultIndieEducationSingleplayerSandbox👍 3,752
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Turing Complete
Oct 2, 2021 · LevelHead
Both: Logic
2D sci-fi educational puzzle simulation, minimalist digital schematic. Building computer hardware, solving logic puzzles and programming assembly.
HardwareLogicAutomationBase BuildingSimulationBuildingProgrammingSandboxEducationHacking👍 5,582
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