Help Ko-fi Join Discord Connect SteamSign in

Games like Patient Zero: Plague Idle

by Game Gangsters

Nodebuster and Idle Colony play most like Patient Zero: Plague Idle. Of the 17 closest games below, most share its incremental and idler.

View on Steam →

Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.

Closest matches

Nodebuster
Aug 13, 2024 · Goblobin
Both: Incremental · Idler · Management
2D incremental idler strategy, abstract minimalist pixel art. Harvesting nodes, buying upgrades and exploring skill trees.
IncrementalCasualStrategyIdlerSimulationArcadeManagement2DExperimentalRelaxing👍 13,862
More like this →
Idle Colony
Dec 16, 2024 · Faith G.
Both: Incremental · Automation · Idler
Top-down 2D incremental colony sim, cute pixel art. Merging fruits, upgrading economy and automating tasks.
IncrementalCasualAutomationStrategyIdlerEconomyManagementColony SimRogueliteBuilding👍 553
More like this →
GridEnergy
Sep 21 · General Studios
Both: Incremental · Idler · Resource Management
Top-down 2D sci-fi incremental simulation strategy, minimalist UI. Resource management, automation and stock market speculation.
IncrementalSimulationStrategyIdlerResource ManagementAutomationManagementEconomyIndie2D
More like this →
Plague Inc: Evolved
Feb 18, 2016 · Ndemic Creations
Both: Outbreak Sim
Top-down 3D modern-day strategy simulation, realistic 3D models. Evolving pathogens, infecting the world and competing in multiplayer.
StrategySimulationOutbreak SimIndieSingleplayerMultiplayerZombiesCasualTacticalReplay Value👍 59,300
More like this →
Fracture Field
Apr 20 · Type Ten
Both: Incremental · Idler · Automation
Top-down 2D idle incremental mining game, pixel graphics. Mining, managing drones and upgrading.
IncrementalIdlerMiningAutomationResource ManagementCasualRelaxingBuildingSingleplayerManagement👍 1,231
More like this →
Swarm Idle
Sep 30 · Omicra Lyrae
Both: Incremental · Idler · Management
Top-down 2D sci-fi incremental idle game, stylized digital art. Command an alien swarm, conquer earth districts and evolve creature lineages.
Early AccessIncrementalRogueliteIdlerAuto BattlerSimulationManagementEconomyStrategyAutomation
More like this →
Sixty Four
Mar 4, 2024 · Oleg Danilov
Both: Incremental · Automation · Resource Management
Isometric 3D incremental clicker strategy, stylized, abstract. Upgrading a factory, automating machines and managing resources.
IncrementalIndieStrategySimulationAutomationResource ManagementManagementIsometricStylizedCrafting👍 1,605
More like this →
Factory Town Idle
Jan 8, 2024 · Erik Asmussen
Both: Idler · Incremental · Resource Management
2D fantasy idle town builder, colorful 2D stylized. Managing economy, automating production and resource management.
CasualIdlerIncrementalMinimalist2DResource ManagementFantasyCity BuilderAutomationColony Sim👍 1,235
More like this →
Revolution Idle
May 1, 2025 · Oni Gaming, Nu Games
Both: Incremental · Idler · Automation
2D sci-fi incremental idle game, minimalist colorful. Multiply, automate and prestige.
IncrementalIdlerFree to PlayCasualSimulationAutomationMinimalist2DIndieManagement
More like this →
Microcivilization
Jan 22 · Ondrej Homola
Both: Incremental · Resource Management · Automation
Side-view 2D historical strategy-clicker blend, pixel-art. Managing population and economy, collecting and merging heroes, overcoming disasters and wars.
IncrementalBase BuildingResource Management4XHistoricalStrategyAutomationInventory ManagementCity BuilderMythology👍 1,437
More like this →
Galactic Overthrow
May 4 · Ace High Arcade
Both: Incremental · Idler · Management
Top-down 2D sci-fi incremental 4x strategy, stylized space art. Explore, develop and conquer.
IncrementalIdlerSimulationCapitalismCasualPoint & Click2DEconomyManagementResource Management
More like this →
(the) Gnorp Apologue
Dec 14, 2023 · Myco
Both: Incremental · Idler · Management
2D fantasy incremental strategy idler, pixel graphics. Acquire and upgrade gnorps, build structures, accumulate shards.
IncrementalIdlerStrategyBuildingEconomyManagementRogueliteCuteMining2D👍 9,618
More like this →
Shelldiver
Nov 16, 2025 · Gagonfe
Both: Incremental · Resource Management · Management
Side-view 2D incremental resource management simulation, colorful and cute. Fishing jellyfish, upgrading equipment and exploring biomes.
IncrementalCasualResource ManagementManagementArcadeIdlerRelaxingSimulation2DColorful👍 17,002
More like this →
Code Blue Idle
Sep 22 · Sulcus Games
Both: Idler · Management · Resource Management
2D modern-day idle management simulation, pixel art. Build a hospital, diagnose patients and hire specialists.
IdlerManagementStrategyResource ManagementSimulationMedical SimCasualIncrementalRelaxingAtmospheric
More like this →
Fortune Mill
Jun 2 · Lavaflame2
Both: Incremental · Idler · Automation
Side-view 2D incremental idler, pixel graphics. Playing mini-games, buying upgrades and automating rooms.
IncrementalIdlerAutomationPixel GraphicsEconomySimulationResource ManagementCasualGamblingLoot👍 3,757
More like this →
Increlution
Oct 13, 2021 · Gniller
Both: Incremental · Idler
2D incremental roguelite strategy RPG, minimalistic text-based. Managing time queues, upgrading skills and exploring.
IncrementalIdlerTime ManagementRogueliteText-BasedMinimalistPoint & ClickEarly AccessIndieStrategy RPG👍 1,238
More like this →
ORACLE: Humanity, Automated
Sep 14 · ZANKYO GAMES
Both: Incremental · Idler · Automation
2D sci-fi idle civilization simulation, minimalist UI. Growing a civilization, automating tasks and unlocking knowledge.
IncrementalStrategyIdlerColony SimArtificial IntelligenceScienceSimulationAutomationGod Game2D
More like this →

Also worth a look

Share some of the same DNA, but further from the original.

Cookie Clicker
Sep 1, 2021 · Orteil, DashNet
Both: Incremental · Idler · Management
2D incremental idler, pixel graphics. Collect cookies, buy upgrades and achievements.
IncrementalIdlerHorrorCasualIndiePixel GraphicsManagementEconomyCollectathonFunny👍 88,140
More like this →