PlayfeedGames like Bioprototype
by Emprom Game
Bioprototype is a 2D sci-fi action roguelike: programming skill logics, combat and building organ combos. Bioweaver and Pathogenic play most like Bioprototype. Of the 12 closest games below, most share its bullet hell, action roguelike and roguelite.
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Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
Bioweaver
Nov 15, 2024 · Emprom Game, Wild Kid Games
Both: Programming · Tactical RPG · Hack and Slash
Top-down 2D sci-fi action RPG, pixel graphics. Programming organ links, mutating organs and fighting creatures.
ProgrammingTactical RPGLooter ShooterAction RPGHack and SlashBullet HellDeckbuildingCharacter CustomizationAutomation2D👍 669Pathogenic
Jul 16 · Aberrant Labs
Both: Roguelike · Bullet Hell · Action Roguelike
Top-down 2D sci-fi action roguelike twin-stick shooter, colorful soft-body organic. Fighting the immune system, evolving via organelle grafting and upgrading via metaprogression.
RoguelikeBullet HellTop-Down ShooterLocal Co-OpBullet HeavenAction RoguelikeDifficultDungeon CrawlerShooterCharacter Customization👍 4,308Nova Drift
Aug 12, 2024 · Chimeric
Both: Bullet Hell · Roguelite · Action Roguelike
Top-down 2D sci-fi action roguelike space shooter, neon arcade aesthetic. Shooting enemies, building custom ship upgrades and surviving waves.
Shoot 'Em UpBullet HellRogueliteArcadeAction RoguelikeArena ShooterAction RPGBullet HeavenShooterRoguelike👍 13,003Vampire Survivors
Oct 20, 2022 · poncle
Both: Action Roguelike · Bullet Hell · Vampires
Top-down 2D fantasy action roguelike bullet hell, pixel graphics. Surviving waves of enemies, collecting gems and items, buying character upgrades.
Action RoguelikeBullet HellVampiresRoguelitePixel Graphics2DIndieSingleplayerCasualRoguelike👍 251,90620 Minutes Till Dawn
Jun 8, 2023 · flanne
Both: Action Roguelike · Bullet Hell · Roguelite
Top-down 2D fantasy action roguelike bullet hell, pixel graphics. Surviving hordes of monsters, creating dynamic builds, collecting upgrades and experience.
Action RoguelikeBullet HellSurvivalRogueliteShoot 'Em UpHorrorTop-Down ShooterCombatPixel GraphicsLovecraftian👍 27,896Slime 3K: Rise Against Despot
Oct 31, 2024 · Konfa Games
Both: Action Roguelike · Bullet Hell · Deckbuilding
Top-down 2D sci-fi action roguelike deckbuilder, pixel art. Surviving enemy onslaughts, deckbuilding with cards, upgrading weapons and traits.
Action RoguelikeBullet HellDeckbuildingRogueliteRoguelike2DShoot 'Em UpTop-Down ShooterHack and SlashShooter👍 1,595Noobs Are Coming
Nov 27, 2025 · Overboy
Both: Action Roguelike · Roguelite · Bullet Hell
Top-down 2D fantasy action roguelike arena shooter, dark cartoonish. Fighting waves of enemies, building synergies with items and upgrading character builds.
Action RoguelikeRogueliteArena ShooterBullet HellRoguelikeDark FantasyReplay ValueActionHack and SlashTop-Down Shooter👍 1,584Soulstone Survivors
Jun 17, 2025 · Game Smithing Limited
Both: Action Roguelike · Roguelite · Bullet Hell
Top-down 2D fantasy action roguelite. Obliterating hordes of enemies, battling colossal bosses and crafting unique weapons.
Bullet HeavenAction RoguelikeRogueliteBullet HellAction RPGRoguelikeCraftingRPGHack and SlashAction👍 25,774Spellbook Demonslayers
Nov 2, 2022 · Xendra
Both: Pixel Graphics · Bullet Hell · Action Roguelike
Top-down 2D fantasy bullet heaven roguelite, pixel graphics. Slaying demons, customizing builds and collecting upgrades.
Dark FantasyTop-DownPixel GraphicsSingleplayerEarly AccessBullet HellAction RoguelikeRPGRogueliteAction👍 1,276Magicraft
Nov 1, 2024 · Wave Games
Both: Action Roguelike · Roguelite · Bullet Hell
Top-down 2D fantasy action roguelike, dark spoof cartoon. Combining spells, battling monsters and solving puzzles.
Action RoguelikeRogueliteBullet HellLooter ShooterRoguelikeStrategy RPGRPGTop-DownDeckbuildingProcedural Generation👍 15,100