Games like Infectious
by Ziggy Makes Games
Infectious is a top-down 2D sci-fi outbreak simulation survival horror: infecting organs, mutating DNA and outrunning immune system. Propa. and Plague Inc: Evolved play most like Infectious. Of the 12 closest games below, most share its outbreak sim.
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Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
Plague Inc: Evolved
Feb 18, 2016 · Ndemic Creations
Both: Outbreak Sim
Top-down 3D modern-day strategy simulation, realistic 3D models. Evolving pathogens, infecting the world and competing in multiplayer.
StrategySimulationOutbreak SimIndieSingleplayerMultiplayerZombiesCasualTacticalReplay Value👍 59,300Thrive
Nov 26, 2021 · Revolutionary Games Studio
Both: Science
Third-person 3D sci-fi evolution simulation sandbox, stylized 3D. Evolving species, surviving environment and competing with species.
SimulationScienceSandboxCharacter CustomizationEducationProcedural GenerationNatureTutorialCasualArtificial Intelligence👍 1,685Extinction Day
Apr 10 · DryGin Studios
Both: Outbreak Sim
Top-down 3D modern-day god game simulation, digital sci-fi interface. Deploying disasters, managing resources and triggering chain reactions.
Outbreak SimReal-Time with PauseSimulationGod GameResource ManagementSandboxPolitical SimManagementDystopian Destruction👍 212Pathologic 2
May 23, 2019 · Ice-Pick Lodge
Both: Survival
First-person 3D survival thriller RPG, surreal and gritty. Managing bodily functions, making difficult choices and fighting a plague.
Story RichAtmosphericChoices MatterDifficultRPGSurvivalImmersive SimDetectivePsychological HorrorSingleplayer👍 9,575They Are Billions
Jun 18, 2019 · Numantian Games
Both: Survival
Isometric 2D post-apocalyptic RTS survival strategy, steampunk digital art. Building colonies, managing resources and fighting infected swarms.
Base BuildingColony SimStrategyZombiesSurvivalRTSTower DefenseCity BuilderSteampunkBuilding👍 46,259Zombie Cure Lab
May 27, 2025 · Thera Bytes GmbH
Both: Science · Outbreak Sim
Isometric 3D post-apocalyptic colony sim and management, stylized 3D. Building a lab, curing zombies and managing resources.
Colony SimZombiesSciencePost-apocalypticResource ManagementBase BuildingOutbreak SimCity BuilderTower DefenseSandbox👍 393