PlayfeedGames like Propa.
by ValarFerys
Propa. is a top-down 2D RTS outbreak simulation: commanding viruses, replicating in cells and evading immune systems. Infectious and Plague Inc: Evolved play most like Propa.. Of the 12 closest games below, most share its rts.
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Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
Plague Inc: Evolved
Feb 18, 2016 · Ndemic Creations
Both: Outbreak Sim
Top-down 3D modern-day strategy simulation, realistic 3D models. Evolving pathogens, infecting the world and competing in multiplayer.
StrategySimulationOutbreak SimIndieSingleplayerMultiplayerZombiesCasualTacticalReplay Value👍 59,300Bio Inc. Redemption
Mar 8, 2018 · DryGin Studios
Both: Medical Sim · Outbreak Sim
2D modern-day medical simulation strategy. Creating diseases, diagnosing and curing illnesses, managing medical strategies.
Medical SimOutbreak SimSimulationStrategyManagementGoreSandboxSingleplayerMultiplayerAtmospheric👍 3,063Pathogenic
Jul 16 · Aberrant Labs
Top-down 2D sci-fi action roguelike twin-stick shooter, colorful soft-body organic. Fighting the immune system, evolving via organelle grafting and upgrading via metaprogression.
RoguelikeBullet HellTop-Down ShooterLocal Co-OpBullet HeavenAction RoguelikeDifficultDungeon CrawlerShooterCharacter Customization👍 4,308Mitos.is: The Game
Jul 29, 2015 · Freakinware Studios
Top-down 2D massively multiplayer survival strategy, minimalist colorful circles. Absorbing smaller cells, evading larger cells and upgrading cellular arsenal.
Free to PlayMultiplayerMassively MultiplayerStrategy2DSurvivalFunnyCasualSimulationPvP👍 174Creeper World 3: Arc Eternal
Mar 27, 2014 · Knuckle Cracker
Both: RTS
Top-down 3D sci-fi strategy simulation, stylized digital. Building fortifications, managing resources and defending against fluid-like substance.
Tower DefenseStrategyIndieRTSSingleplayerSci-fiReal-Time with PauseSimulationBase BuildingLevel Editor👍 4,102Infection Free Zone
Apr 11, 2024 · Jutsu Games
Both: RTS
Top-down 3D post-apocalyptic city builder survival strategy, realistic 3D graphics. Base building, resource management and defending against zombies.
Early AccessBase BuildingPost-apocalypticZombiesCity BuilderStrategyManagementSurvivalSimulationRTS👍 16,621Zombie Cure Lab
May 27, 2025 · Thera Bytes GmbH
Both: Outbreak Sim
Isometric 3D post-apocalyptic colony sim and management, stylized 3D. Building a lab, curing zombies and managing resources.
Colony SimZombiesSciencePost-apocalypticResource ManagementBase BuildingOutbreak SimCity BuilderTower DefenseSandbox👍 393