Games like The Book of Plagues
by DiaMMax Games
The Book of Plagues is a 2D historical medical outbreak simulation: diagnose ailments, treat diseases and make moral decisions. Bio Inc. Redemption and War Hospital play most like The Book of Plagues. Of the 12 closest games below, most share its outbreak sim.
View on Steam · $6.99 →
Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
Bio Inc. Redemption
Mar 8, 2018 · DryGin Studios
Both: Medical Sim · Outbreak Sim
2D modern-day medical simulation strategy. Creating diseases, diagnosing and curing illnesses, managing medical strategies.
Medical SimOutbreak SimSimulationStrategyManagementGoreSandboxSingleplayerMultiplayerAtmospheric👍 3,063War Hospital
Jan 11, 2024 · Brave Lamb Studio S.A.
Both: Medical Sim
Top-down 3D historical medical management strategy sim, stylized realistic. Managing medical supplies, treating patients and managing hospital staff.
ManagementMedical SimMilitaryStrategyHistoricalStylizedTop-DownGrand StrategyMultiple EndingsChoices Matter👍 1,014Omen Exitio: Plague
Mar 5, 2018 · Tiny Bull Studios
Both: Visual Novel
2D historical Lovecraftian interactive fiction, hand-drawn illustrations. Making choices, reading text and investigating mystery.
LovecraftianIndieInteractive FictionChoices MatterStory RichAdventureChoose Your Own AdventureVisual NovelCasualText-Based👍 495GlobalQuarantine
Jun 2, 2025 · ValarFerys
Both: Medical Sim · Idler · Outbreak Sim
2D modern-day simulation strategy, flat 2D illustration. Managing global health, building headquarters and making political decisions.
CasualSimulationStrategyMedical SimIdlerPolitical SimOutbreak Sim2DText-BasedDystopianPlague Inc: Evolved
Feb 18, 2016 · Ndemic Creations
Both: Outbreak Sim
Top-down 3D modern-day strategy simulation, realistic 3D models. Evolving pathogens, infecting the world and competing in multiplayer.
StrategySimulationOutbreak SimIndieSingleplayerMultiplayerZombiesCasualTacticalReplay Value👍 59,300The Life and Suffering of Sir Brante
Mar 4, 2021 · Sever, Schisma Games
Both: Visual Novel · Medieval
2D fantasy narrative RPG, black and white sketch. Making choices, developing character skills and reading story.
Choices MatterStory RichRPGInteractive FictionChoose Your Own AdventureVisual NovelText-BasedMedievalIndieSingleplayer👍 8,15960 Seconds! Reatomized
Jul 25, 2019 · Robot Gentleman
Both: Dark Humor · Outbreak Sim
2D post-apocalyptic survival strategy adventure, hand-drawn 2D graphics. Scavenging supplies, managing resources and making survival choices.
2DChoose Your Own AdventureDark HumorTurn-Based TacticsStrategyExplorationOutbreak SimPoint & ClickImmersive SimText-Based👍 18,412