PlayfeedGames like Science Monster: Grafted Heart
by JIELIN
Science Monster: Grafted Heart is a top-down 2D post-apocalyptic action roguelite survival: grafting organs, surviving combat and building mutations. Pathogenic and Necrosmith play most like Science Monster: Grafted Heart. Of the 11 closest games below, most share its action roguelike, bullet hell and top-down shooter.
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Ranked by how similar the games actually are, not by sales. Released and Price are remembered for next time.
Closest matches
Pathogenic
Jul 16 · Aberrant Labs
Both: Bullet Hell · Top-Down Shooter · Action Roguelike
Top-down 2D sci-fi action roguelike twin-stick shooter, colorful soft-body organic. Fighting the immune system, evolving via organelle grafting and upgrading via metaprogression.
RoguelikeBullet HellTop-Down ShooterLocal Co-OpBullet HeavenAction RoguelikeDifficultDungeon CrawlerShooterCharacter Customization👍 4,308Genome Guardian
May 7, 2024 · Alpherior
Both: Action Roguelike · Shooter · Top-Down Shooter
Top-down 2D sci-fi action roguelike shooter, colorful bioluminescent. Shooting microbes, combining DNA for weapons and researching permanent upgrades.
Action RoguelikeShooterRogueliteGun CustomizationRoguelikeTop-Down ShooterSurvivalScienceAtmosphericColorful👍 711Nova Drift
Aug 12, 2024 · Chimeric
Both: Action Roguelike · Bullet Hell · Shooter
Top-down 2D sci-fi action roguelike space shooter, neon arcade aesthetic. Shooting enemies, building custom ship upgrades and surviving waves.
Action RoguelikeArena ShooterBullet HellShoot 'Em UpRogueliteArcadeShooter2DRoguelikeAction RPG👍 13,003Nuclear Throne
Dec 5, 2015 · Vlambeer
Both: Action Roguelike · Bullet Hell · Top-Down Shooter
2D post-apocalyptic top-down shooter roguelike, pixel graphics. Fighting through wastelands, collecting radiation, mutating limbs and abilities.
Action RoguelikeRoguelikePixel GraphicsIndieDifficultBullet HellActionRogueliteTop-Down ShooterGreat Soundtrack👍 15,056Graveyard Gunslingers
Nov 8, 2024 · PyroPhysics
Both: Action Roguelike · Bullet Hell · Top-Down Shooter
3D post-apocalyptic action roguelike top-down shooter, stylized 3D. Surviving zombie hordes, gathering resources and upgrading skills.
ActionAction RoguelikeBullet HellShoot 'Em UpTop-Down ShooterTwin Stick ShooterRogueliteTop-Down3DAtmospheric👍 225The Last Stand: Aftermath
Nov 16, 2021 · Con Artist Games
Both: Post-apocalyptic · Top-Down Shooter · Shooter
Top-down 3D post-apocalyptic action adventure roguelite shooter, tense and moody. Fighting zombies, scavenging materials and crafting weapons.
ZombiesSurvivalPost-apocalypticTop-Down ShooterRogueliteShooterAction RoguelikeSingleplayerAdventureTop-Down👍 6,116Deep Rock Galactic: Survivor
Sep 17, 2025 · Funday Games
Both: Action Roguelike · Bullet Hell · Top-Down Shooter
Top-down 3D sci-fi action roguelike, stylized 3D. Kill aliens, mine riches and upgrade gear.
DwarvesAction RoguelikeBullet HeavenRogueliteBullet HellTop-Down ShooterPvETop-DownArena ShooterProcedural Generation👍 46,417Starforged Legacy
Jun 1 · Second Shift Games
Both: Action Roguelike · Top-Down Shooter · Bullet Hell
Top-down 3D sci-fi action roguelike bullet heaven. Combat against swarms, ship customization and galactic navigation.
Early AccessAction RoguelikeTop-Down ShooterBullet HellBullet HeavenRoguelitePvEArcadeRoguelikeStrategy👍 17420 Minutes Till Dawn
Jun 8, 2023 · flanne
Both: Action Roguelike · Bullet Hell · Top-Down Shooter
Top-down 2D fantasy action roguelike bullet hell, pixel graphics. Surviving hordes of monsters, creating dynamic builds, collecting upgrades and experience.
Action RoguelikeBullet HellSurvivalRogueliteShoot 'Em UpHorrorTop-Down ShooterCombatPixel GraphicsLovecraftian👍 27,896Halls of Torment
Sep 24, 2024 · Chasing Carrots
Both: Action Roguelike · Bullet Hell
Top-down 2D fantasy action roguelike horde survival, pre-rendered retro pixel. Fighting waves of enemies, collecting items and abilities, completing quests.
Action RoguelikeRogueliteBullet HellPixel GraphicsDark FantasyAction RPGRoguelikeActionRPGArcade👍 30,777